Due to ongoing funding uncertainties, we are currently unable to answer individual inquiries regarding prospective graduate student positions or other openings in the lab.
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California Institute of Technology
Division of Biology and Biological Engineering
MC 114-96 | 1200 E. California Blvd.,
Pasadena, CA 91125
(626) 395-8351 phone
Our laboratory is interested in immune recognition of viral pathogens. We are investigating the immune responses against HIV-1 and other viruses, most recently SARS-CoV-2, in order to develop improved therapeutics and/or vaccines. We use X-ray crystallography, electron microscopy, and biochemistry to study pathogen glycoproteins and host immune proteins. Using structural information and alternate antibody architectures, we are engineering antibody-based reagents with increased potency and breadth. We are also investigating the structural correlates of potent antibody-mediated neutralization of HIV-1, SARS-CoV-2, and hepatitis C virus to better understand what leads to naturally-occurring potent neutralizing antibodies.Anthony West has developed Variant Database, a SARS-CoV-2 mutation pattern query tool, 06/2021
HIVRADP01 2024 Project:
Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1Antibodies-Animation, Visualizing HIV-1: Andy DeLaitsch, 2025
-Wolf Prize: Pamela Bjorkman, 2025
-Pearl Meister Greengard Prize: Pamela Bjorkman, 2021
- Webinar: Pamela Bjorkman: Viruses, Antiviral and Vaccines, 04/2020
-The HIV Life Cycle
-Donate in memory of Will Lange, 2016
–Watson Lecture, Pamela Bjorkman, 2015
–TEDxCaltech: New Anti-HIV Agents, 2013
–Traveling with Purpose - Volunteering in India, 2012
–World AIDS Day - News Conf on KNBC-TV, 2012
–LA Theatre Works: Rosalind Franklin, 2011
–Magnus Hoffmann wins Clauser Doctoral Prize, 2022
–Rachel Galimidi wins Clauser Doctoral Prize, 2016
–Gwen Owens, Crystals in space, 2013
